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Data Sciences International conscious blood pressure data
(A – C) 24-hour systolic and diastolic <t>blood</t> <t>pressure,</t> and heart rate of Eln +/+ and Eln +/− female mice before and 4 weeks after OVX. (C) A decrease in heart rate was observed in both groups after OVX. (D) Pulse pressure, an indicator of arterial stiffness, increased in both groups after OVX. <t>Data</t> are presented as mean ± SEM; Baseline Eln +/+ (n=10), Baseline Eln +/− (n=13), OVX Eln +/+ (n=8), OVX Eln +/− (n=8). * P <0.05, between-group comparison, analyzed using a two-way ANOVA mixed model with Sidak post hoc multiple comparison tests.
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1) Product Images from "Ovarian Hormones Moderate Systolic Hypertension in Female Eln Haploinsufficient Mice"

Article Title: Ovarian Hormones Moderate Systolic Hypertension in Female Eln Haploinsufficient Mice

Journal: bioRxiv

doi: 10.1101/2025.11.18.689164

(A – C) 24-hour systolic and diastolic blood pressure, and heart rate of Eln +/+ and Eln +/− female mice before and 4 weeks after OVX. (C) A decrease in heart rate was observed in both groups after OVX. (D) Pulse pressure, an indicator of arterial stiffness, increased in both groups after OVX. Data are presented as mean ± SEM; Baseline Eln +/+ (n=10), Baseline Eln +/− (n=13), OVX Eln +/+ (n=8), OVX Eln +/− (n=8). * P <0.05, between-group comparison, analyzed using a two-way ANOVA mixed model with Sidak post hoc multiple comparison tests.
Figure Legend Snippet: (A – C) 24-hour systolic and diastolic blood pressure, and heart rate of Eln +/+ and Eln +/− female mice before and 4 weeks after OVX. (C) A decrease in heart rate was observed in both groups after OVX. (D) Pulse pressure, an indicator of arterial stiffness, increased in both groups after OVX. Data are presented as mean ± SEM; Baseline Eln +/+ (n=10), Baseline Eln +/− (n=13), OVX Eln +/+ (n=8), OVX Eln +/− (n=8). * P <0.05, between-group comparison, analyzed using a two-way ANOVA mixed model with Sidak post hoc multiple comparison tests.

Techniques Used: Comparison

(A) Renal blood flow (RBF) was significantly increased in OVX Eln +/− mice, while (B) renal vascular resistance (RVR) was similar among the different groups but trended lower Eln +/− mice after OVX. (C) GFR trended low in Eln +/+ OVX mice but was similar among the other groups. (D) Filtration fraction (FF), calculated as the ratio of GFR to RPF, trended low in sham Eln +/− mice and following OVX in both Eln +/+ and Eln +/− mice. Pressure-natriuresis curves generated with daytime (E) and nighttime (F) systolic blood pressure (SBP) and overnight urine sodium excretion rates of pre– and post-OVX in Eln +/+ (n= 4-8) and Eln +/− (n= 5–6) mice. Data are presented as mean ± SEM. UvNa + , urinary sodium excretion rate. LKW – Left kidney weight. ** P <0.01
Figure Legend Snippet: (A) Renal blood flow (RBF) was significantly increased in OVX Eln +/− mice, while (B) renal vascular resistance (RVR) was similar among the different groups but trended lower Eln +/− mice after OVX. (C) GFR trended low in Eln +/+ OVX mice but was similar among the other groups. (D) Filtration fraction (FF), calculated as the ratio of GFR to RPF, trended low in sham Eln +/− mice and following OVX in both Eln +/+ and Eln +/− mice. Pressure-natriuresis curves generated with daytime (E) and nighttime (F) systolic blood pressure (SBP) and overnight urine sodium excretion rates of pre– and post-OVX in Eln +/+ (n= 4-8) and Eln +/− (n= 5–6) mice. Data are presented as mean ± SEM. UvNa + , urinary sodium excretion rate. LKW – Left kidney weight. ** P <0.01

Techniques Used: Filtration, Generated

Low-salt diet slightly lowered SBP in Eln +/+ , thereby enhancing the difference in SBP between (A) sham and (B) OVX mice relative to their respective cohorts. Diastolic blood pressure in (C) sham and (D) OVX mice was similar. Data are presented as mean ± SEM, * P <0.05, between-group comparison, analyzed using a two-way ANOVA mixed model with Sidak post hoc multiple comparison tests.
Figure Legend Snippet: Low-salt diet slightly lowered SBP in Eln +/+ , thereby enhancing the difference in SBP between (A) sham and (B) OVX mice relative to their respective cohorts. Diastolic blood pressure in (C) sham and (D) OVX mice was similar. Data are presented as mean ± SEM, * P <0.05, between-group comparison, analyzed using a two-way ANOVA mixed model with Sidak post hoc multiple comparison tests.

Techniques Used: Comparison

Baseline measurements were collected for ∼1 hour prior to captopril administration (10 mg/kg, i.p.). Average values over 30 minutes preceding the injection were subtracted from pre– and postinjection blood pressure and heart rate values. Δ Systolic blood pressure in sham (A) and OVX mice (B). Δ Diastolic blood pressure in sham (C) and OVX (D) mice. Δ Heart rate in sham (E) and OVX (F) mice. Data are presented as mean ± SEM. The time of injection is denoted by red arrow.
Figure Legend Snippet: Baseline measurements were collected for ∼1 hour prior to captopril administration (10 mg/kg, i.p.). Average values over 30 minutes preceding the injection were subtracted from pre– and postinjection blood pressure and heart rate values. Δ Systolic blood pressure in sham (A) and OVX mice (B). Δ Diastolic blood pressure in sham (C) and OVX (D) mice. Δ Heart rate in sham (E) and OVX (F) mice. Data are presented as mean ± SEM. The time of injection is denoted by red arrow.

Techniques Used: Injection

Amiloride was administered daily (1.5 mg/kg, i.p.) for 3 days at least 4 weeks after ovariectomy (OVX) and at the end of 10 days of low salt diet in wild type ( Eln +/+ , n=5) and Eln +/− (n=6) mice. Twenty-hour systolic (SBP, A & B) and diastolic (DBP, C & D) blood pressure was measured one day before and on the last day of amiloride injection. Overnight urine flow rate (E), osmolality (F), sodium excretion rate (G), and potassium excretion rate (H) before and after 3-day administration of amiloride in Eln +/+ and Eln +/− OVX mice. Data points in bar graphs represent individual animals in each experimental group and genotype. Values in line graphs and bar graphs are expressed as mean ± SEM. ** P <0.01, between-group comparison, analyzed using two-way ANOVA mixed model with Sîdak post hoc multiple comparison tests. NS, not significant.
Figure Legend Snippet: Amiloride was administered daily (1.5 mg/kg, i.p.) for 3 days at least 4 weeks after ovariectomy (OVX) and at the end of 10 days of low salt diet in wild type ( Eln +/+ , n=5) and Eln +/− (n=6) mice. Twenty-hour systolic (SBP, A & B) and diastolic (DBP, C & D) blood pressure was measured one day before and on the last day of amiloride injection. Overnight urine flow rate (E), osmolality (F), sodium excretion rate (G), and potassium excretion rate (H) before and after 3-day administration of amiloride in Eln +/+ and Eln +/− OVX mice. Data points in bar graphs represent individual animals in each experimental group and genotype. Values in line graphs and bar graphs are expressed as mean ± SEM. ** P <0.01, between-group comparison, analyzed using two-way ANOVA mixed model with Sîdak post hoc multiple comparison tests. NS, not significant.

Techniques Used: Injection, Comparison



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Data Sciences International conscious blood pressure data
(A – C) 24-hour systolic and diastolic <t>blood</t> <t>pressure,</t> and heart rate of Eln +/+ and Eln +/− female mice before and 4 weeks after OVX. (C) A decrease in heart rate was observed in both groups after OVX. (D) Pulse pressure, an indicator of arterial stiffness, increased in both groups after OVX. <t>Data</t> are presented as mean ± SEM; Baseline Eln +/+ (n=10), Baseline Eln +/− (n=13), OVX Eln +/+ (n=8), OVX Eln +/− (n=8). * P <0.05, between-group comparison, analyzed using a two-way ANOVA mixed model with Sidak post hoc multiple comparison tests.
Conscious Blood Pressure Data, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/conscious+blood+pressure+data/bio_rxiv__2025__11__18__689164-50-0-9?v=Data+Sciences+International
Average 86 stars, based on 1 article reviews
conscious blood pressure data - by Bioz Stars, 2026-06
86/100 stars
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(A – C) 24-hour systolic and diastolic blood pressure, and heart rate of Eln +/+ and Eln +/− female mice before and 4 weeks after OVX. (C) A decrease in heart rate was observed in both groups after OVX. (D) Pulse pressure, an indicator of arterial stiffness, increased in both groups after OVX. Data are presented as mean ± SEM; Baseline Eln +/+ (n=10), Baseline Eln +/− (n=13), OVX Eln +/+ (n=8), OVX Eln +/− (n=8). * P <0.05, between-group comparison, analyzed using a two-way ANOVA mixed model with Sidak post hoc multiple comparison tests.

Journal: bioRxiv

Article Title: Ovarian Hormones Moderate Systolic Hypertension in Female Eln Haploinsufficient Mice

doi: 10.1101/2025.11.18.689164

Figure Lengend Snippet: (A – C) 24-hour systolic and diastolic blood pressure, and heart rate of Eln +/+ and Eln +/− female mice before and 4 weeks after OVX. (C) A decrease in heart rate was observed in both groups after OVX. (D) Pulse pressure, an indicator of arterial stiffness, increased in both groups after OVX. Data are presented as mean ± SEM; Baseline Eln +/+ (n=10), Baseline Eln +/− (n=13), OVX Eln +/+ (n=8), OVX Eln +/− (n=8). * P <0.05, between-group comparison, analyzed using a two-way ANOVA mixed model with Sidak post hoc multiple comparison tests.

Article Snippet: Conscious blood pressure data were acquired using radiotelemetry (HD-X10, Data Sciences International, St. Paul, MN), as described previously , .

Techniques: Comparison

(A) Renal blood flow (RBF) was significantly increased in OVX Eln +/− mice, while (B) renal vascular resistance (RVR) was similar among the different groups but trended lower Eln +/− mice after OVX. (C) GFR trended low in Eln +/+ OVX mice but was similar among the other groups. (D) Filtration fraction (FF), calculated as the ratio of GFR to RPF, trended low in sham Eln +/− mice and following OVX in both Eln +/+ and Eln +/− mice. Pressure-natriuresis curves generated with daytime (E) and nighttime (F) systolic blood pressure (SBP) and overnight urine sodium excretion rates of pre– and post-OVX in Eln +/+ (n= 4-8) and Eln +/− (n= 5–6) mice. Data are presented as mean ± SEM. UvNa + , urinary sodium excretion rate. LKW – Left kidney weight. ** P <0.01

Journal: bioRxiv

Article Title: Ovarian Hormones Moderate Systolic Hypertension in Female Eln Haploinsufficient Mice

doi: 10.1101/2025.11.18.689164

Figure Lengend Snippet: (A) Renal blood flow (RBF) was significantly increased in OVX Eln +/− mice, while (B) renal vascular resistance (RVR) was similar among the different groups but trended lower Eln +/− mice after OVX. (C) GFR trended low in Eln +/+ OVX mice but was similar among the other groups. (D) Filtration fraction (FF), calculated as the ratio of GFR to RPF, trended low in sham Eln +/− mice and following OVX in both Eln +/+ and Eln +/− mice. Pressure-natriuresis curves generated with daytime (E) and nighttime (F) systolic blood pressure (SBP) and overnight urine sodium excretion rates of pre– and post-OVX in Eln +/+ (n= 4-8) and Eln +/− (n= 5–6) mice. Data are presented as mean ± SEM. UvNa + , urinary sodium excretion rate. LKW – Left kidney weight. ** P <0.01

Article Snippet: Conscious blood pressure data were acquired using radiotelemetry (HD-X10, Data Sciences International, St. Paul, MN), as described previously , .

Techniques: Filtration, Generated

Low-salt diet slightly lowered SBP in Eln +/+ , thereby enhancing the difference in SBP between (A) sham and (B) OVX mice relative to their respective cohorts. Diastolic blood pressure in (C) sham and (D) OVX mice was similar. Data are presented as mean ± SEM, * P <0.05, between-group comparison, analyzed using a two-way ANOVA mixed model with Sidak post hoc multiple comparison tests.

Journal: bioRxiv

Article Title: Ovarian Hormones Moderate Systolic Hypertension in Female Eln Haploinsufficient Mice

doi: 10.1101/2025.11.18.689164

Figure Lengend Snippet: Low-salt diet slightly lowered SBP in Eln +/+ , thereby enhancing the difference in SBP between (A) sham and (B) OVX mice relative to their respective cohorts. Diastolic blood pressure in (C) sham and (D) OVX mice was similar. Data are presented as mean ± SEM, * P <0.05, between-group comparison, analyzed using a two-way ANOVA mixed model with Sidak post hoc multiple comparison tests.

Article Snippet: Conscious blood pressure data were acquired using radiotelemetry (HD-X10, Data Sciences International, St. Paul, MN), as described previously , .

Techniques: Comparison

Baseline measurements were collected for ∼1 hour prior to captopril administration (10 mg/kg, i.p.). Average values over 30 minutes preceding the injection were subtracted from pre– and postinjection blood pressure and heart rate values. Δ Systolic blood pressure in sham (A) and OVX mice (B). Δ Diastolic blood pressure in sham (C) and OVX (D) mice. Δ Heart rate in sham (E) and OVX (F) mice. Data are presented as mean ± SEM. The time of injection is denoted by red arrow.

Journal: bioRxiv

Article Title: Ovarian Hormones Moderate Systolic Hypertension in Female Eln Haploinsufficient Mice

doi: 10.1101/2025.11.18.689164

Figure Lengend Snippet: Baseline measurements were collected for ∼1 hour prior to captopril administration (10 mg/kg, i.p.). Average values over 30 minutes preceding the injection were subtracted from pre– and postinjection blood pressure and heart rate values. Δ Systolic blood pressure in sham (A) and OVX mice (B). Δ Diastolic blood pressure in sham (C) and OVX (D) mice. Δ Heart rate in sham (E) and OVX (F) mice. Data are presented as mean ± SEM. The time of injection is denoted by red arrow.

Article Snippet: Conscious blood pressure data were acquired using radiotelemetry (HD-X10, Data Sciences International, St. Paul, MN), as described previously , .

Techniques: Injection

Amiloride was administered daily (1.5 mg/kg, i.p.) for 3 days at least 4 weeks after ovariectomy (OVX) and at the end of 10 days of low salt diet in wild type ( Eln +/+ , n=5) and Eln +/− (n=6) mice. Twenty-hour systolic (SBP, A & B) and diastolic (DBP, C & D) blood pressure was measured one day before and on the last day of amiloride injection. Overnight urine flow rate (E), osmolality (F), sodium excretion rate (G), and potassium excretion rate (H) before and after 3-day administration of amiloride in Eln +/+ and Eln +/− OVX mice. Data points in bar graphs represent individual animals in each experimental group and genotype. Values in line graphs and bar graphs are expressed as mean ± SEM. ** P <0.01, between-group comparison, analyzed using two-way ANOVA mixed model with Sîdak post hoc multiple comparison tests. NS, not significant.

Journal: bioRxiv

Article Title: Ovarian Hormones Moderate Systolic Hypertension in Female Eln Haploinsufficient Mice

doi: 10.1101/2025.11.18.689164

Figure Lengend Snippet: Amiloride was administered daily (1.5 mg/kg, i.p.) for 3 days at least 4 weeks after ovariectomy (OVX) and at the end of 10 days of low salt diet in wild type ( Eln +/+ , n=5) and Eln +/− (n=6) mice. Twenty-hour systolic (SBP, A & B) and diastolic (DBP, C & D) blood pressure was measured one day before and on the last day of amiloride injection. Overnight urine flow rate (E), osmolality (F), sodium excretion rate (G), and potassium excretion rate (H) before and after 3-day administration of amiloride in Eln +/+ and Eln +/− OVX mice. Data points in bar graphs represent individual animals in each experimental group and genotype. Values in line graphs and bar graphs are expressed as mean ± SEM. ** P <0.01, between-group comparison, analyzed using two-way ANOVA mixed model with Sîdak post hoc multiple comparison tests. NS, not significant.

Article Snippet: Conscious blood pressure data were acquired using radiotelemetry (HD-X10, Data Sciences International, St. Paul, MN), as described previously , .

Techniques: Injection, Comparison